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The importance of GPR119 in the fat-induced incretin secretion is demonstrated by the impaired incretin signaling displayed by transgenic animals deficient for this protein only in PG expressing intestinal cells

Urticaria presented the shortest onset time at a median of 8 days, and pruritic rash showed the longest at 52 days

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Plasma was collected from the submandibular vein at baseline and at indicated times

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